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Health Benefits of Sorghum

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Sorghum May Inhibit Cancer Tumor Growth

Compounds in sorghum called 3-Deoxyanthoxyanins (3-DXA) are present in darker-colored sorgums, and to a lesser extent in white sorghum. Scientists at the University of Missouri tested extracts of black, red, and white sorghums and found that all three extracts had strong antiproliferative activity against human colon cancer cells.
Journal of Agricultural & Food Chemistry. 2009 Mar 11;57(5):1797-804

Sorghum May Protect Against Diabetes and Insulin Resistance

Advanced glycation endproducts (AGEs) are increasingly implicated in the complications of diabetes. A study from the University of Georgia Neutraceutical Research Libraries showed that sorghum brans with a high phenolic content and high anti-oxidant properties inhibit protein glycation, whereas wheat, rice or oat bran, and low-phenolic sorghum bran did not. These results suggest that “certain varieties of  sorghum bran may affect critical biological processes that are important in diabetes and insulin resistance.”
Phytotherapy Research. 2008 Aug;22(8):1052-6

Sorghum is Safe for People with Celiac Disease

Up to one percent of the U.S. population (and about ½% worldwide) is believed to have Celiac Disease, an autoimmune reaction to gluten proteins found in wheat, barley and rye. While sorghum has long been thought safe for celiacs, no clinical testing had been done until researchers in Italy made a study. First, they conducted laboratory tests; after those tests established the likely safety, they fed celiac patients sorghum-derived food products for five days. The patients experienced no symptoms and the level of disease markers (anti-transglutaminase antibodies) was unchanged at the end of the five-day period.
Clinical Nutrition. 2007 Dec;26(6):799-805. Epub 2007 Aug 24

Sorghum May Help Manage Cholesterol

Scientists at the University of Nebraska observed that sorghum is a rich source of phytochemicals, and decided to study sorghum’s potential for managing cholesterol. They fed different levels of sorghum lipids to hamsters for four weeks, and found that the healthy fats in sorghum significantly reduced “bad” (non-HDL) cholesterol.  Reductions ranged from 18% in hamsters fed a diet including 0.5% sorghum lipids, to 69% in hamsters fed a diet including 5% sorghum lipids.  “Good” (HDL) cholesterol was not affected. Researchers concluded that “grain sorghum contains beneficial components that could be used as food ingredients or dietary supplements to manage cholesterol levels in humans.